发明名称 |
NUCLEIC ACID ENCODING NEUROPEPTIDE Y/PEPTIDE YY (Y2) RECEPTORS AND USES THEREOF |
摘要 |
This invention provides isolated nucleic acid molecules encoding Y2 receptors, an isolated, purified Y2 receptor protein, vectors comprising isolated nucleic acid molecules encoding Y2 receptors, mammalian, insect, bacterial and yeast cells comprising such vectors, antibodies directed to the Y2 receptors, nucleic acid probes useful for detecting nucleic acid encoding Y2 receptors, antisense oligonucleotides complementary to unique sequences of a nucleic acid molecule which encodes a Y2 receptor, pharmaceutical compounds related to the Y2 receptors, and nonhuman transgenic animals which express nucleic acid encoding a normal or mutant Y2 receptor. This invention further provides methods for determining ligand binding, detecting expression, drug screening, and methods of treatment involving Y2 receptors.
|
申请公布号 |
WO9521245(A1) |
申请公布日期 |
1995.08.10 |
申请号 |
WO1995US01469 |
申请日期 |
1995.02.03 |
申请人 |
SYNAPTIC PHARMACEUTICAL CORPORATION;GERALD, CHRISTOPHE;WALKER, MARY, W.;BRANCHEK, THERESA;WEINSHANK, RICHARD |
发明人 |
GERALD, CHRISTOPHE;WALKER, MARY, W.;BRANCHEK, THERESA;WEINSHANK, RICHARD |
分类号 |
A01K67/027;A61K31/70;A61K38/00;A61K45/00;A61K48/00;A61P1/00;A61P25/00;A61P25/08;C07H21/04;C07K14/705;C07K16/28;C12N5/00;C12N5/10;C12N15/09;C12P21/08;C12Q1/68;C12R1/91;G01N33/566;(IPC1-7):C12N5/10;C12N5/16;C12N7/01;C12N15/00;C12N15/10;C12N15/11;C12N15/12;C12N15/16;C12N15/63;C07H21/00;C07K14/00;C07K14/72 |
主分类号 |
A01K67/027 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|