REPRODUCTION OF GENETIC INFORMATION IN ANIMAL CELL AND RETAINABLE NUCLEOTIDE SEQUENCE

摘要

The invention relates to the use of a DNA fragment comprising a sequence of the 3' end of the IE1 gene of the AcNPV baculovirus, optionally combined with a DNA fragment comprising a sequence located upstream of the promoter of the aforementioned IE1 gene, for obtaining vectors permitting replication and maintenance of genetic information in animal cells. The invention also encompasses the episomal vectors obtained, as well as transformed cells comprising the aforementioned vectors.