| 发明名称 |
Biologically active n-acylprolydipeptides having antiamnestic, antihypoxic and anorexigenic effects |
| 摘要 |
A novel class of substances of N-acyl-prolyldipeptides, which possess psychotropic activity and particularly facilitate learning and memory are described. The N-acyl-prolyldipeptides of the invention have the formula: <IMAGE> (1) wherein R1=(C4-C5) alkyl, cycloalkyl, aralkyl, or aryl; R2=H1 (C1-C4) alkyl, carbamidoalkyl, or carbalkoxyalkyl; R3=NH2, NH(alkyl), N(alkyl)2, OH, or alkoxy; and n=0-3, preferably 0-2.
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| 申请公布号 |
US5439930(A) |
申请公布日期 |
1995.08.08 |
| 申请号 |
US19920960905 |
申请日期 |
1992.10.14 |
| 申请人 |
RUSSIAN-AMERICAN INSTITUTE FOR NEW DRUG DEVELOPMENT |
发明人 |
SEREDENIN, SERGEI B.;VORONINA, TATIANA A.;GUDASHEVA, TATIANA A.;OSTROVSKAYA, RITA U.;ROZANTSEV, GRIGORI G.;SKOLDINOV, ALEXANDER P.;TROPHIMOV, SERGEI S.;HALIKAS, JAMES A.;GARIBOVA, TAISIJA L. |
| 分类号 |
A61K38/00;C07D207/16;C07K5/078;(IPC1-7):A61K31/40;C07D207/12 |
主分类号 |
A61K38/00 |
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