| 发明名称 |
IMMUNOCONJUGATES FOR CANCER DIAGNOSIS AND THERAPY |
| 摘要 |
Immunoconjugates of an antibody to a 22 KD breast tumor associated antigen were prepared. Cytotoxic immunoconjugates such as gelonin-15A8 antibody conjugate are useful for treating proliferative cell diseases such as breast carcinoma and cervical carcinoma as well as other tumors which bear the 15A8 antigen. Detectably labeled compositions for diagnosis of such diseases are also disclosed.
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| 申请公布号 |
CA1336497(C) |
申请公布日期 |
1995.08.01 |
| 申请号 |
CA19890604974 |
申请日期 |
1989.07.06 |
| 申请人 |
RESEARCH DEVELOPMENT FOUNDATION |
发明人 |
ROSENBLUM, MICHAEL G.;DULBECCO, RENATO;ALLEN, W. ROSS |
| 分类号 |
A61K45/00;A61K38/00;A61K39/395;A61K47/48;A61K49/00;A61P35/00;C07K1/113;C07K14/00;C07K14/415;C07K16/00;C07K16/30;C07K19/00;C12P21/08;G01N33/574;(IPC1-7):A61K47/48 |
主分类号 |
A61K45/00 |
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