摘要 |
Epidermal growth factor inhibitors of formula (1), where: at least one, and as many as three of A-E are nitrogen, with the remaining atom(s) carbon, or any two contiguous positions in A-E taken together can be a single heteroatom, N, O or S, in which case one of the two remaining atoms must be carbon, and the other can be either carbon or nitrogen; X = O, S, NH or NR7, such that R7 = lower alkyl (1-4 carbon atoms), OH, NH2, lower alkoxy (1-4 carbon atoms) or lower monoalkylamino (1-4 carbon atoms); n = 0, 1, 2.
|
申请人 |
WARNER-LAMBERT COMPANY |
发明人 |
BRIDGES, ALEXANDER JAMES;DENNY, WILLIAM ALEXANDER;FRY, DAVID;KRAKER, ALAN;MEYER, ROBERT FREDERICK;REWCASTLE, GORDON WILLIAM;THOMPSON, ANDREW MARK |