发明名称 |
GANE CODING 3-ACYLATION ENZYME OF MACROLIDE ANTIBIOTIC SUBSTANCE |
摘要 |
PURPOSE:To obtain the subject gene capable of producing a 3-acylated macrolide antibiotic substance at a low cost. CONSTITUTION:This gene is a DNA fragment containing a gene acyA coding a 3-site acylating enzyme for a macrolide antibiotic substance, originated from a microbial strain belonging to the genus Streptomyces, having a size of about 1.8 kb or about 3.2 kb and characterized by a restriction enzyme map of the figure. The present invention also relates to a restriction DNA fragment obtained from the DNA fragment by a restriction enzyme treatment. |
申请公布号 |
JPH07177892(A) |
申请公布日期 |
1995.07.18 |
申请号 |
JP19910048753 |
申请日期 |
1991.02.22 |
申请人 |
MERCIAN CORP |
发明人 |
ARISAWA AKIRA;KAWAMURA NAOTO;KOJIMA IKUO;OKAMURA KAZUHIKO;TONE HIROSHI;OKAMOTO ROKURO |
分类号 |
C12N15/09;C12N1/21;C12N9/18;C12N15/54;C12N15/76;C12P19/62;C12R1/465;C12R1/54 |
主分类号 |
C12N15/09 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|