| 摘要 |
<p>Cpds. (I) where Z = C4-5 alkyl, cycloalkyl, alkoxy or cycloalkoxy; lower alkylmercapto, alkylsulphinyl or alkylsulphonyl; Ph, PhCH2, PhCH2O, lower alkanoyl, aroyl, CF3, OH, acyloxy, COOH or CN; or carbamyl optionally subst. by lower alkyl groups; Z' = H or (when Z = OH or COOH) also halogen, lower alkyl or lower alkoxy; Y = C1-3 straight or branched hydrocarbon residue; R1 = saturated or unsaturated C2-8 alkyl; C4-8 alkyl interrupted by O or S; PhCH2, phenyl-ethyl, cyclohexylmethyl or cyclohexylethyl; cyclohexyl subst. by Me, Et, Pr, i-Pr, MeO, EtO, PrO or i-PrO; C5-8 cycloalkyl; or saturated or unsaturated cycloalkyl or cycloalkylmethyl with 4-5 ring C atoms and contng. an O or S atom in the ring; and their salts. Strong and long-acting hypoglycaemics. N-(4-(2-(4-BuO-benzamido) ethyl)-benzenesulphonyl)-N'-cyclohexylurea, m.p. 197-9 deg. (from MeOH/dioxan.).</p> |
