发明名称 |
Method of treatment of hormone-unresponsive metastatic prostate cancer |
摘要 |
Prostate cancer particularly hormone-unresponsive metastatic prostate cancer, is treated by cyclophosphamide or other normally substantially inactive agent. Potentiation of the anti-cancer activity and amelioration of cyclophosphamide-associated toxicity is achieved by an initial intravenous infusion of DPPE over an approximately one hour period prior to cyclophosphamide treatment.
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申请公布号 |
US5432168(A) |
申请公布日期 |
1995.07.11 |
申请号 |
US19930173047 |
申请日期 |
1993.12.27 |
申请人 |
UNIVERSITY OF MANITOBA |
发明人 |
BRANDES, LORNE J. |
分类号 |
C07D295/08;A61K31/135;A61K31/22;A61K31/282;A61K31/495;A61K31/505;A61K31/535;A61K31/5375;A61K31/66;A61K31/675;A61K31/704;A61K31/7072;A61K33/24;A61K45/06;A61P15/00;A61P35/00;A61P43/00;(IPC1-7):A61K31/675 |
主分类号 |
C07D295/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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