| 发明名称 |
NOVEL HUMAN .BETA.2 INTEGRIN ALPHA SUBUNIT |
| 摘要 |
DNA encoding a novel human .beta.2 integrin .alpha. subunit polypeptide, designated .alpha.d, is disclosed along with methods and materials for production of the same by recombinant procedures. Fusion proteins are also disclosed which include extracellular .alpha.d protein fragments, .alpha.d I domain fragments or full length .alpha.d polypeptides and human immunoglobulin constant regions. Binding molecules specific for .alpha.d are also disclosed as useful for modulating the biological activities of .alpha.d. DNA from other species which show homology to human .alpha.d encoding sequences are also disclosed.
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| 申请公布号 |
CA2156622(A1) |
申请公布日期 |
1995.06.29 |
| 申请号 |
CA19942156622 |
申请日期 |
1994.12.21 |
| 申请人 |
ICOS CORPORATION |
发明人 |
GALLATIN, W. MICHAEL;VAN DER VIEREN, MONICA |
| 分类号 |
A01K67/027;A61K38/00;A61K39/395;C07H19/00;C07H21/00;C07H21/04;C07K1/00;C07K2/00;C07K4/00;C07K7/06;C07K7/08;C07K14/47;C07K14/705;C07K16/18;C07K16/28;C07K19/00;C12N1/20;C12N5/00;C12N5/10;C12N15/00;C12N15/02;C12N15/09;C12N15/12;C12P21/02;C12P21/06;C12P21/08;C12Q1/00;C12Q1/68;C12R1/91;G01N33/53;G01N33/577;(IPC1-7):C12N15/12;C07K16/42;G01N33/566;C12N15/64 |
主分类号 |
A01K67/027 |
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