| 发明名称 |
MONOCLONAL ANTIBODIES SPECIFIC FOR PHF-TAU, HYBRIDOMAS SECRETING THEM, ANTIGEN RECOGNITION BY THESE ANTIBODIES AND THEIR APPLICATIONS |
| 摘要 |
The present invention relates more particularly to a monoclonal antibody which forms an immunological complex with a phosphorylated epitope of an antigen belonging to abnormally phosphorylated tau (PHF-tau) residing in the region spanning positions (143-254), and with said monoclonal antibody being characterized by the fact that it is capable of specifically detecting abnormally phosphorylated tau protein (PHF-tau) in cerebrospinal fluid (CSF).
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| 申请公布号 |
WO9517429(A1) |
申请公布日期 |
1995.06.29 |
| 申请号 |
WO1994EP04146 |
申请日期 |
1994.12.14 |
| 申请人 |
INNOGENETICS N.V.;VANDERMEEREN, MARC;VANMECHELEN, EUGEEN;VAN DE VOORDE, ANDRE |
发明人 |
VANDERMEEREN, MARC;VANMECHELEN, EUGEEN;VAN DE VOORDE, ANDRE |
| 分类号 |
G01N33/53;C07K7/06;C07K14/47;C07K16/18;C12N5/20;C12N15/02;C12P21/08;C12R1/91;G01N33/577;G01N33/68;(IPC1-7):C07K16/18 |
主分类号 |
G01N33/53 |
| 代理机构 |
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