Methods for detecting intraocular pressure-related tissue damage in vivo

摘要

This invention relates to an animal model for human ocular disease, particularly glaucoma. The invention provides methods for determining the causes of human ocular diseases, and specifically provides methods for the anatomical, histochemical and molecular biological evaluation of the effects of elevated intraocular pressure on various tissues in mammalian eyes in vivo. The invention also provides methods for non-invasively measuring intraocular pressure and for evaluating the efficacy of treatment stategies for glaucoma involving glaucoma-relieving drugs.