| 摘要 |
<p>The new cyclopropyl derivatives have formula (I) wherein R is cyclopropyl or methylcyclopropyl. The preparation process comprises reacting 2,6-dibromohexanoyl chloride with 2,6-dimethylanyline in the presence of a base at 0°-25 °C to give 2,6-dibromohexanoyl-2,6-dimethylanilide which subsequently is caused to react with R-NH2 (wherein R is as defined hereabove) at 70-100 °C to give the cyclopropyl derivatives having formula (I). The compounds (I) can be applied as antiarithmic agents and as local anaesthetic agents.</p> |
