发明名称 Methods for inhibiting smooth muscle cell proliferation and restinosis.
摘要 Methods of inhibiting smooth muscle cell proliferation and restinosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula <CHEM> or <CHEM> wherein R1 and R3 are independently hydrogen, -CH3, <CHEM> or <CHEM> wherein Ar is optionally substituted phenyl; R2 is <CHEM> and R4 is hydrogen or -OR1, and pharmaceutically acceptable salts and solvates thereof. Also provided is a method for inhibiting restinosis.
申请公布号 EP0652003(A1) 申请公布日期 1995.05.10
申请号 EP19940307526 申请日期 1994.10.13
申请人 ELI LILLY AND COMPANY 发明人 CULLINAN, GEORGE JOSEPH;SINGH, JAI PAL;WOOD, DAN LEE
分类号 C07D295/08;A61K31/38;A61K31/381;A61K31/40;A61K31/402;A61K31/4025;A61K31/445;A61K31/4453;A61K31/4535;A61K31/55;A61P9/10;A61P9/14;C07D333/64 主分类号 C07D295/08
代理机构 代理人
主权项
地址