发明名称 |
Methods for inhibiting smooth muscle cell proliferation and restinosis. |
摘要 |
Methods of inhibiting smooth muscle cell proliferation and restinosis comprising administering to a human or other mammal in need of treatment an effective amount of a compound having the formula <CHEM> or <CHEM> wherein R1 and R3 are independently hydrogen, -CH3, <CHEM> or <CHEM> wherein Ar is optionally substituted phenyl; R2 is <CHEM> and R4 is hydrogen or -OR1, and pharmaceutically acceptable salts and solvates thereof. Also provided is a method for inhibiting restinosis. |
申请公布号 |
EP0652003(A1) |
申请公布日期 |
1995.05.10 |
申请号 |
EP19940307526 |
申请日期 |
1994.10.13 |
申请人 |
ELI LILLY AND COMPANY |
发明人 |
CULLINAN, GEORGE JOSEPH;SINGH, JAI PAL;WOOD, DAN LEE |
分类号 |
C07D295/08;A61K31/38;A61K31/381;A61K31/40;A61K31/402;A61K31/4025;A61K31/445;A61K31/4453;A61K31/4535;A61K31/55;A61P9/10;A61P9/14;C07D333/64 |
主分类号 |
C07D295/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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