| 摘要 |
<p>There is disclosed compounds and methods for the synthesis of pantethine, pantetheine, and derivatives thereof. The methods utilize crystalline derivatives of the above compounds as intermediates which readily permit purification by recrystallization, and thus allow the generation of highly pure products. The synthesis utilizes the 1,3-diol functional group present in pantothenic acid to produce the crystalline derivatives by formation of ketal intermediates. Subsequent hydrolisis of the ketal intermediates yields pantethine or pantetheine in highly pure form.</p> |
