Hydrochloride salts of heterocyclic spiro compounds

摘要

Hydrochloride salts of heterocyclic spiro compounds are provided and can be represented by the following general formula: <IMAGE> wherein A represents piperidine or N alkyl piperidine or N alkylene attached to a non adjacent piperidine ring carbon, X is S or O, Y is carbonyl, thiocarbonyl, methylene, R5 methylene, <IMAGE> alk in which R1 to R3,R6,R7 are H or alkyl, R4 is H, alkyl, COOH, or ester, or -C alkyl, R5 is halo, OH,SH, O alkyl, S alkyl, O acyl or S acyl, and Z, and Z2 are O or S. The above compounds act upon muscarinic acetylcholine receptors, thereby activating the acetylcholine nervous functions in the central nervous system.