New 4'-epi-4'-amino anthracyclines

摘要

Anthracycline glycosides having the general formula 1 and 2: <IMAGE> 1 <IMAGE> 2 wherein R1 is selected from the group consisting of hydrogen, fluorine, hydroxy or amino; R2 and R3 represent hydroxy or one of R2 and R3 is a hydrogen atom, a nitro or an amino group and the other of R2 and R3 is a HYDROXY group, exhibit activity against LoVo and LoVo/Dx in vitro.