NUCLEOTIDE VECTOR, COMPOSITION CONTAINING SUCH VECTOR AND VACCINE FOR IMMUNIZATION AGAINST HEPATITIS
摘要
<p>Nucleotide vector comprising at least one gene or one complementary DNA coding for at least a portion of a protein of a virus, and a promoter providing for the expression of such gene in muscle cells. The gene may be the S gene of the hepatitis B virus. A vaccine preparation containing said bare DNA is injected into the host previously treated with a substance capable of inducing a coagulating necrosis of the muscle fibers.</p>
申请公布号
WO9511307(A1)
申请公布日期
1995.04.27
申请号
WO1994FR00483
申请日期
1994.04.27
申请人
INSTITUT PASTEUR;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M;UNIVERSITE D'OTTAWA;DAVIS, HEATHER, LYNN;WHALEN, ROBERT, GERALD;MICHEL, MARIE-LOUISE