发明名称 |
INDOLE DERIVATIVE |
摘要 |
An indole derivative represented by general formula (I), each isomer thereof or a mixture of the isomers, a physiologically acceptable salt thereof, and a solvate thereof, wherein R<1> represents (a) or (b); R<2> represents optionally substituted phenyl; and R<3> represents hydrogen, methyl or ethyl. This derivative has a potent and selective antagonism against intestinal 5-HT3 receptors when compared with known 5-HT3 antagonists and can well retain the effect for long, so that it is particularly useful for preventing or treating digestive tract disorders such as irritable bowel syndrome and diarrhea.
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申请公布号 |
WO9511245(A1) |
申请公布日期 |
1995.04.27 |
申请号 |
WO1994JP01769 |
申请日期 |
1994.10.20 |
申请人 |
TOKYO TANABE COMPANY LIMITED;TSUCHIYA, SHINJI;YASUDA, NOBOYUKI;FUKUZAKI, ATSUSHI |
发明人 |
TSUCHIYA, SHINJI;YASUDA, NOBOYUKI;FUKUZAKI, ATSUSHI |
分类号 |
C07D471/16;(IPC1-7):C07D471/06;A61K31/475 |
主分类号 |
C07D471/16 |
代理机构 |
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代理人 |
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地址 |
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