CONTROL COMPOSITIONS FOR DETERMINATION OF MOLECULAR CYTOGENETIC ABNORMALITIES WITH DNA PROBES

摘要

Quality control compositions suitable as sample specimens to measure performance of DNA probe tests which determine cytogenetic abnormalities, such as chromosome copy number, of cells in a tissue sample are disclosed. The control compositions comprise a suspension of fixed cells having an articifial concentration of cells exhibiting chromosome specific aneuploidy in one or more specific chromosomes.