| 发明名称 |
Aplha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors |
| 摘要 |
Disclosed are compounds, compositions and methods for inhibiting interleukin - 1 beta protease activity, the compounds having the formula (I) defined herein. |
| 申请公布号 |
AU6347394(A) |
申请公布日期 |
1995.04.27 |
| 申请号 |
AU19940063473 |
申请日期 |
1994.06.02 |
| 申请人 |
STERLING WINTHROP INC. |
发明人 |
DENTON W. HOYER;ROLAND E. DOLLE;STANLEY J. SCHMIDT;TINA MORGAN ROSS;PRASAD V. CHATURVEDULA;CATHERINE P. PROUTY;MOHAMED M.A. AWAD;JASBIR SINGH;TODD L. GRAYBILL;GARY J. SPEIER;DAVID A. WHIPPLE |
| 分类号 |
C12N9/99;A61K31/397;A61K31/415;A61K31/42;A61K31/421;A61K31/47;A61K31/472;A61K31/535;A61K31/5375;A61K31/5377;A61K31/55;A61K38/00;A61P29/00;A61P37/00;A61P43/00;C07D205/04;C07D207/38;C07D209/12;C07D215/14;C07D217/16;C07D223/08;C07D231/20;C07D231/22;C07D261/12;C07D263/06;C07D265/06;C07D265/30;C07D311/46;C07D311/50;C07D311/56;C07D401/12;C07D409/12;C07D413/04;C07D417/12;C07D453/02;C07D471/04;C07K5/02;C07K5/06;C07K5/062;C07K5/078;C07K5/08;C07K5/083;C07K5/09;C07K5/097 |
主分类号 |
C12N9/99 |
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