| 摘要 |
A compound having pharmaceutical activity, of the formula <IMAGE> (I) in which A is hydrogen or -(CR1R2)xR3 where x is 0 or 1 to 4, R1 and R2 are each hydrogen or C1-4 alkyl and R3 is -CN, -COOH, tetrazolyl or -CONHSO2R4 where R4 is optionally substituted phenyl, and <IMAGE> <IMAGE> <IMAGE> where R5 and R6 are each hydrogen, C1-4 alkyl or -(CR1R2)xR3 where x, R1, R2 and R3 are as defined above, and R7 is hydrogen, C1-4 alkyl or -(CR1R2)xR3 where x is 1 to 4, and R1, R2 and R3 are as defined above; provided that when A is hydrogen at least one of R5, R6 and R7 is -(CR1R2)xR3, and provided that when <IMAGE> A is -(CR1R2)xR3 and x is 1 to 4 then R3 is -CONHSO2R4; and salts and esters thereof.
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