发明名称 |
ANTI-PARAMYXOVIRUS SCREENING METHOD AND VACCINE |
摘要 |
A method is provided for detecting whether a test composition can inhibit cell fusion mediated by paramyxovirus infection. A method is also provided for identifying an antiviral peptide capable of inhibiting paramyxovirus-induced cell fusion. The methods are based on the discovery that the hemagglutination and fusion-inducing proteins of paramyxoviruses interact to form a complex termed HN:F, that is prerequisite to cell fusion. Antibodies to HN:F provide a novel means of providing improved immunity against paramyxovirus infection.
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申请公布号 |
WO9510632(A1) |
申请公布日期 |
1995.04.20 |
申请号 |
WO1994US11746 |
申请日期 |
1994.10.11 |
申请人 |
EMORY UNIVERSITY |
发明人 |
COMPANS, RICHARD, WILLIAM |
分类号 |
A61K38/00;A61K39/00;C07K14/115;C07K16/10;G01N33/50;G01N33/569;(IPC1-7):C12Q1/70;A61K39/12 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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