Verfahren zur enzymatischen Herstellung von GRF(1-44)NH2.
摘要
GRF(1-44)-NH2 is prepared by the trypsin catalyzed enzymatic coupling of Leu-NH2 to GRF(1-43)-OH. The latter compound may be obtained by recombinant DNA synthesis. Thus the present method provides an economical way to obtain the clinically important GRF(1-44)-NH2.
申请公布号
DE69108192(D1)
申请公布日期
1995.04.20
申请号
DE1991608192
申请日期
1991.12.04
申请人
F. HOFFMANN-LA ROCHE AG, BASEL, CH
发明人
FELIX, ARTHUR MARTIN, WEST CALDWELL, N.J. 07006, US;HEIMER, EDGAR PHILIP, NUTLEY, N.J. 07110, US
