PROTEIN- OR PEPTIDE-COCHLEATE VACCINES AND METHODS OF IMMUNIZING USING THE SAME

摘要

The present disclosure relates to a vaccine comprising a biologically effective dosage amount of a protein- or peptide-cochleate, wherein said protein- or peptide-cochleate comprises the following components: a) a protein or peptide component to which an immune response is elicited, b) a negatively charged lipid component, and c) a divalent cation component. The present invention also provides a method of immunizing a host, comprising administering a biologically effective amount of the above-described protein- or peptide-cochleate. Advantageously, the vaccine can be administered orally.