4-Arylmethyl-1H-pyrazol-3-amines, their salts, and their preparation

摘要

For the first time there are described 4-aryl(hetaryl)methyl-1H-pyrazole-3-amines and their salts, in particular their hydrochlorides, which themselves are useful as antibacterial agents, anxiolytic agents and sedatives or as intermediates for the preparation of 3-aryl(hetaryl)methylpyrazolo[1,5-a]pyrimidines or 8-aryl(hetaryl)methylpyrazolo[5,1-c][1,2,4]triazines which have an anticonvulsive, antiepileptic, muscle-relaxing, anxiolytic or sedative action and which were described in the simultaneously filed patent application of the applicant under the title "Arylmethyl-substituted pyrazolo-azines, in particular 3-arylmethyl pyrazolo[1,5-a]pyrimidines, and the preparation of 8-arylmethyl-pyrazolo[5,1-c][1,2,4]triazines", filed under the internal file reference AZ: E/P 003.