发明名称 |
Controlled, sustained release delivery system for smoking cessation |
摘要 |
A drug delivery system useful in aiding individuals in the cessation of smoking or chewing nicotine containing products is described. The delivery system includes a physical constraint modulation system (PCMS TM ) containing lobeline. The drug delivery system is capable of delivering lobeline to an individual in a controlled, sustained release manner and providing long-term therapeutic levels of lobeline to the individual. The delivery of lobeline in such a manner reduces or eliminates the individual's smoking or chewing habit. The PCMS may be a biodegradable polymer containing the lobeline capable of subcutaneous or intramuscular injection or implantation into the individual or may be part of a transdermal patch containing lobeline. Also described are methods of using the drug delivery systems and kits containing the drug delivery systems.
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申请公布号 |
US5403595(A) |
申请公布日期 |
1995.04.04 |
申请号 |
US19930135847 |
申请日期 |
1993.10.13 |
申请人 |
DYNAGEN, INC. |
发明人 |
KITCHELL, JUDITH P.;MUNI, INDU A.;BOYER, YVONNE N. |
分类号 |
A61K9/00;A61K9/16;A61K9/70;A61K31/439;A61K31/44;A61K31/4425;A61K31/445;A61K31/4545;A61K31/455;A61K31/465;G01N33/52;(IPC1-7):A61K9/50;A61K9/48 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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