发明名称 |
IMPROVED METHODS FOR PREPARING BIS-IMIDE COMPOUNDS |
摘要 |
This invention relates to methods for preparing bis-imide compounds, in particular, bis-naphthalimides which are useful as cancer chemotherapeutic agents. The methods comprise the reaction of one or more anhydrides and a polyamine under heating conditions effective to reduce the formation of side products. The heating step can be conducted in a continuous flow system.
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申请公布号 |
WO9508539(A1) |
申请公布日期 |
1995.03.30 |
申请号 |
WO1994US10105 |
申请日期 |
1994.09.15 |
申请人 |
THE DU PONT MERCK PHARMACEUTICAL COMPANY |
发明人 |
SUN, JUNG-HUI;MEIER, WALTER, ERICH;PARK, CHUNG-HO;MATOS, JOSE, RICARDO |
分类号 |
C07D221/14;C07D221/18;(IPC1-7):C07D221/14 |
主分类号 |
C07D221/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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