Compounds of the formula: <IMAGE> I wherein a is a single bond and b is a double bond; or a is a double bond and b is a single bond; and enantiomers thereof; or a pharmaceutically acceptable salt thereof are described. These compounds can improve lipoprotein profile of dyslipidemic patients and generate an anti-atherogenic lipoprotein profile of normolipidemic individuals. In addition, inhibition of CETP activity may be useful as antifertility agents.
申请公布号
AU7716694(A)
申请公布日期
1995.03.22
申请号
AU19940077166
申请日期
1994.08.31
申请人
HARBOR BRANCH OCEANOGRAPHIC INSTITUTION, INC.
发明人
STEPHEN J COVAL;VINCENT P. GULLO;ANN C. HORAN;MAHESH G. PATEL;SHIRLEY A POMPONI