摘要 |
A polyether antibiotic material is prepared by forming discrete polyether antibiotic-containing agglomerates which are separable from an aqueous medium, by producing a polyether antibiotic through cultivation of a polyether antibiotic-producing microorganism in a generally aqueous nutrient-containing fermentation broth under conditions wherein at the end of fermentation, a saponifiable lipid is present in the broth in a sufficient amount to form discrete agglomerates with polyether antibiotic in the fermentation broth, whereupon the agglomerates are separated from the broth.
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