发明名称 NEW IMIDAZOLE DERIVATIVES HAVING AGONISTIC OR ANTAGONISTIC ACTIVITY ON THE HISTAMINE H3 RECEPTOR
摘要 The invention relates to new imidazole derivatives of formula (I) having agonistic and antagonistic activity on the histamine H3-receptor. More in particular the invention concerns 4- and 5-substituted aminoalkyl imidazoles and their derivatives. The invention further relates to the synthesis of these compounds, pharmaceutical compositions comprising the said compounds or pharmacological salts thereof, and the use of the compounds as agents having biological activity on the histamine H3-receptor or for the preparation of a pharmaceutical composition.
申请公布号 WO9506037(A1) 申请公布日期 1995.03.02
申请号 WO1994NL00206 申请日期 1994.08.29
申请人 VRIJE UNIVERSITEIT;VOLLINGA, ROELANT, CHRISTIAAN;MENGE, WIRO, MICHAEL, PETRUS, BERNARDUS;TIMMERMAN, HENDRIK 发明人 VOLLINGA, ROELANT, CHRISTIAAN;MENGE, WIRO, MICHAEL, PETRUS, BERNARDUS;TIMMERMAN, HENDRIK
分类号 C07D233/54;C07D401/04;C07D401/06;(IPC1-7):C07D233/54;A61K31/415 主分类号 C07D233/54
代理机构 代理人
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