发明名称 Athferth vith ath f beta fram stöthuga kristallagerth fínkornottra efna
摘要 PCT No. PCT/SE94/00780 Sec. 371 Date Jan. 30, 1995 Sec. 102(e) Date Jan. 30, 1995 PCT Filed Aug. 25, 1994 PCT Pub. No. WO95/05805 PCT Pub. Date Mar. 2, 1995The present invention relates to a process for providing a stable crystallinic form to a fine-grained substance or a substance mixture, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of such a substance or a substance mixture, by a) in case of a substance mixture, preparing a homogenous mixture of the substances; b) micronizing, direct precipitating or diminishing by any conventional method the substance or substance mixture into a particle size required for inhalation, the particle size being less than 10 mu m; c) optionally preparing a homogenous mixture of the desired substances when each substance has been introduced from stage b) as separate fine-grained particles; d) conditioning said substance or substance mixture by treatment with a water containing vapor phase in a controlled fashion; and e) drying.
申请公布号 IS4199(A) 申请公布日期 1995.02.28
申请号 IS19940004199 申请日期 1994.08.08
申请人 ASTRA AKTIEBOLAG 发明人 EVA ANN-CHRISTIN TROFAST
分类号 A61K9/00;A61K9/14;A61K9/72;A61K31/137;A61K31/41;A61K31/4245;A61K31/425;A61K31/426;A61K31/433;A61K31/44;A61K31/496;A61K31/505;A61K47/12;A61P29/00;A61P43/00;B01J2/28;C07C45/68;C07C49/753;C07C65/40;C07C69/94;C07C205/45;C07C225/22;C07C233/33;C07C255/56;C07C311/08;C07D213/28;C07D213/30;C07D213/38;C07D213/40;C07D239/42;C07D271/06;C07D271/10;C07D277/24;C07D285/12;C07D333/38;C07D413/04;(IPC1-7):A61K9/72;A61J3/02 主分类号 A61K9/00
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