| 发明名称 |
ESTROGENIC COMPOUNDS AS ANTI-MITOTIC AGENTS |
| 摘要 |
The application discloses methods of making medicaments for treating mammalian diseases characterized by abnormal cell mitosis by administering estradiol derivatives including those comprising colchicine or combretastatin A-4 structural motifs of general formulae found above in a dosage sufficient to inhibit cell mitosis. The application discloses novel compounds used in the methods.
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| 申请公布号 |
CA2168850(A1) |
申请公布日期 |
1995.02.16 |
| 申请号 |
CA19942168850 |
申请日期 |
1994.08.02 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION (THE) |
发明人 |
D'AMATO, ROBERT JOHN;FOLKMAN, MOSES JUDAH |
| 分类号 |
A61K31/05;A61K31/27;A61K31/56;A61K31/565;A61K31/567;A61K31/59;A61P43/00;C07J1/00;C07J3/00;C07J5/00;C07J7/00;C07J9/00;C07J13/00;C07J31/00;C07J41/00;C07J63/00;(IPC1-7):C07J1/00;C07J73/00 |
主分类号 |
A61K31/05 |
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