发明名称 |
SELECTIN BINDING GLYCOPEPTIDES |
摘要 |
Glyco-amino acids or glycopeptides that have three-dimensionally stable configuration for the presentation of functional groups, fucose, or an analogue or derivative thereof, covalently linked to an amino acid or peptide with a free carboxylic acid group, that facilitate binding between those groups and receptors on selectins, represented by general structural formula (I) as shown in claim 1. The glycopeptides of structural formula (I) can be administered to a subject to treat inflammation.
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申请公布号 |
WO9504751(A1) |
申请公布日期 |
1995.02.16 |
申请号 |
WO1994US08713 |
申请日期 |
1994.08.01 |
申请人 |
GLYCOMED INCORPORATED |
发明人 |
TANG, PENG, CHO;LEVY, DANIEL, EMIL;HOLME, KEVIN, ROSS;ABBAS, SAEED, ABDALLA |
分类号 |
G01N33/50;A61K38/00;A61P29/00;A61P35/00;A61P37/06;C07D309/10;C07D405/06;C07D405/12;C07H21/04;C07K5/078;C07K9/00;G01N33/566;(IPC1-7):C07K1/00 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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