发明名称 |
METHOD OF NON-SPECTROSCOPIC, NON-DISPLAYING IN VIVO DETERMINATION OF NMR CONCENTRATION - A DETECTABLE XENOBIOTIC COMPOUND |
摘要 |
Methods wherein the concentration of NMR-detectable xenobiotic compounds may be determined in living subjects by in vivo measurement of one or more magnetic resonance signals. In preferred embodiments, the present invention provides a method for evaluating, in vivo, the clearance rate of a xenobiotic compound from a living subject, thereby providing a noninvasive method for determining the status of the excretory organs of the subject, and a method for determining the proper dosing regimen of a pharmacologically active compound to be administered to the subject. |
申请公布号 |
CZ9400898(A3) |
申请公布日期 |
1995.02.15 |
申请号 |
CZ19940000898 |
申请日期 |
1994.04.14 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
TWEEDLE MICHAEL F.;STRAUSS HARRY WILLIAM;NUNN ADRIAN D. |
分类号 |
A61B5/055;A61K49/00;A61K49/06;G01N24/08;G01R33/28;G01R33/465;(IPC1-7):G01N24/08 |
主分类号 |
A61B5/055 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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