发明名称 Fused heteroalkylene quinolinamines
摘要 There are disclosed compounds having the formula <IMAGE> wherein n is 1-4; R is hydrogen, loweralkyl or loweralkylcarbonyl; R1 is hydrogen, loweralkyl, loweralkylcarbonyl, aryl, diloweralkylaminoloweralkyl, arylloweralkyl, diarylloweralkyl, oxygen-bridged arylloweralkyl, or oxygen-bridged diaryllowerallyl; A is a direct bond or (CHR3)m, m being 1-3; X is hydrogen, loweralkyl, cycloalkyl, loweralkoxy, halogen, hydroxy, nitro, trifluoromethyl, formyl, loweralkylcarbonyl, arylcarbonyl, -SH, loweralkylthio, -NHCOR4 or -NR5R6, R4 being hydrogen or loweralkyl, and R5 and R6 being independently hydrogen, loweralkyl or cycloalkyl; Y is O, S or NR7; and each R2, each R3 and R7 are independently hydrogen or loweralkyl, or taken two at a time form a methylene or ethylene group constituting a part of a ring of at least five atoms; stereo, optical and geometrical isomers thereof, and pharmaceutically acceptable acid addition salts thereof, which are useful for enhancing memory.
申请公布号 US5389629(A) 申请公布日期 1995.02.14
申请号 US19910639432 申请日期 1991.01.10
申请人 HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED 发明人 SHUTSKE, GREGORY M.;EFFLAND, RICHARD C.
分类号 C07D491/04;C07D491/044;C07D495/04;(IPC1-7):C07D487/02;A61K31/55 主分类号 C07D491/04
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