发明名称 |
1,4-dihydropyridine compounds |
摘要 |
The compounds are 2,4-disubstituted 3-ethoxycarbonyl 5-methoxycarbonyl 6-methyl 1,4-dihydropyridines in their dextrorotatory form, useful to potentiate the activity of cytotoxic agents and to increase the sensitivity of tumor cells to antitumor agents. A compound disclosed is d-2-{[2-(2-(N-p-nitrobenzylamino)ethoxy)ethoxy]methyl}-4-(2,3-dichlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine.
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申请公布号 |
US5389644(A) |
申请公布日期 |
1995.02.14 |
申请号 |
US19930013297 |
申请日期 |
1993.02.04 |
申请人 |
ADIR ET COMPAGNIE |
发明人 |
PEGLION, JEAN-LOUIS;AASSSI, GHANEM;PIERRE, ALAIN;KRAUS-BERTHIER, LAURENCE;GUILBAUD, NICOLAS;VILAINE, JEAN-PAUL |
分类号 |
A61K31/455;A61K31/4427;A61K31/4433;A61P35/00;A61P43/00;C07D211/90;C07D401/12;C07D407/12;C07D409/12;C07D413/12;C07D417/12;(IPC1-7):A61K31/44 |
主分类号 |
A61K31/455 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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