| 摘要 |
PCT No. PCT/FR91/00055 Sec. 371 Date Jul. 31, 1992 Sec. 102(e) Date Jul. 31, 1992 PCT Filed Jan. 30, 1991 PCT Pub. No. WO91/11189 PCT Pub. Date Aug. 8, 1989.The present invention relates to the use of an alpha -tocopherol phosphate, especially in its dl or d form, or an ester thereof, of the general formula <IMAGE> (I) in which: R1 is a hydrogen atom, an alkyl radical having from 1 to 4 carbon atoms, such as the methyl or ethyl radical in particular, or an alpha -tocopheryl radical; and R2 is a hydrogen atom, an alkyl radical having from 1 to 4 carbon atoms, such as a methyl or ethyl radical in particular, or an oxyethylene chain of the formula <IMAGE> in which R3 and R4 independently are a hydrogen atom or a methyl radical and n is an integer greater than or equal to 1, or a salt thereof, for preparing a pharmaceutical, dermatological or cosmetic composition for the prevention or treatment of allergic manifestations such as skin allergy or bronchial asthma, or inflammatory manifestations, or for the prevention or treatment of the harmful effects of free radicals.
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