摘要 |
<p>A method for administering hemoglobin to a patient in need thereof comprising a pharmacokinetics administration wherein a hemoglobin containing composition is first administered as a loading dose calculated upon the concentration of hemoglobin desired in said patient and said patient's apparent volume of distribution; and thereafter administered as a maintenance dose calculated to maintain a steady-state hemoglobin level in the patient. The maintenance dose can be administered as a continuous infusion or as single doses. The method is useful for the administration of all blood components and all blood sources and can be performed in emergency, trauma, presurgical, surgical or post-operative situations wherever it is desirable to replace, control, elevate or maintain a blood component, especially hemoglobin level in a patient.</p> |