发明名称 |
Protein encapsulated insoluble gas microspheres and their preparation and use as ultrasonic imaging agents |
摘要 |
Encapsulated gas microspheres having improved pressure resistance and stability are made by: mixing an aqueous solution of a filmogenic protein such as human serum albumin with a water insoluble gas such as perfluoropropane and subjecting the mixture to ultrasonic or mechanical cavitation in the absence of oxygen in an apparatus that is closed to the atmosphere. |
申请公布号 |
AU7218494(A) |
申请公布日期 |
1995.01.24 |
申请号 |
AU19940072184 |
申请日期 |
1994.07.01 |
申请人 |
MOLECULAR BIOSYSTEMS, INC. |
发明人 |
KAREL J LAMBERT;SHEILA BENAY PODELL;EDWARD G. JABLONSKI;CARL HULLE;KENNETH HAMILTON;ROLF LOHRMANN |
分类号 |
A61K49/00;A61K49/22;B01J13/02;B01J13/04 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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