发明名称 |
Polyvalent peptide pharmaceutical applications |
摘要 |
High affinity linked, branched or linear repeat peptides containing two or more biological-function domains and at least one medically useful metal ion-binding domain are labeled with medically useful metal ions for use in a variety of diseases and pathologic conditions, including diagnosis and treatment of diseases. Such peptides include high affinity chemotactic peptides containing a biological-function domain which includes at least two linked N-formyl-MLF (SEQ. ID NO. 2) sequences and high affinity repeat and branched peptides containing two or more YIGSR (SEQ. ID NO. 1) sequences. |
申请公布号 |
AU7216994(A) |
申请公布日期 |
1995.01.24 |
申请号 |
AU19940072169 |
申请日期 |
1994.07.01 |
申请人 |
RHOMED INCORPORATED |
发明人 |
BUCK A. RHODES;PAUL O ZAMORA;RICHARD J FREER;SHUBH D SHARMA |
分类号 |
A61K38/00;A61K49/08;A61K51/08;A61K51/10;C07K5/083;C07K7/06;C07K14/00;C07K14/52;C07K14/655;C07K14/78 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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