Quinoline and naphthyridine prodrugs

摘要

The following 3-carboxaldehyde quinolines and naphthyridines have antibacterial activity wherein A, Y, R, and R2 are as defined herein. These compounds are particularly suitable for administration by injection. A specific example of such compound is 1-cyclopropyl-6-fluoro-7-[(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]hept -2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxaldehyde.