摘要 |
A process for producing an alpha -alkoxyiminophenylacetonitrile represented by general formula [III], (wherein R<1>, R<2>, R<3> and Y are each as defined in the specification) by reacting an alkali metal salt of an alpha -hydroxyiminophenylacetonitrile, represented by general formula [I], (wherein R<1>, R<2>, Y and A are each as defined in the specification) with a dialkyl sulfate represented by the general formula [II]: (R<3>)2SO4, (wherein R<3> is as defined in the specification) in the presence of a phase transfer catalyst in a solvent mixture composed of a hydrocarbon solvent and water. It is possible by using the above catalyst and solvent mixture to inhibit the formation of a nitrone derivative as a by-product to thereby produce a highly pure alkoxyimino compound in a high yield.
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申请人 |
SHIONOGI & CO., LTD.;SUMITOMO CHEMICAL COMPANY, LIMITED;TAKASE, AKIRA;KAI, HIROYUKI;MASUI, MORIYASU;MASUMOTO, KATUHISA;NAKAMURA, AKIHIKO;KIYOSHIMA, YUJIRO;SASAKI, MIKIO |
发明人 |
TAKASE, AKIRA;KAI, HIROYUKI;MASUI, MORIYASU;MASUMOTO, KATUHISA;NAKAMURA, AKIHIKO;KIYOSHIMA, YUJIRO;SASAKI, MIKIO |