| 摘要 |
<p>The invention relates to a method for the production of optically active glycerol derivatives having general formula (I), (IIa) or (IIb) where X represents an easily removable protecting group Y or a hydrogen atom, the protecting group Y being an unsubstituted or a substituted benzyl or trityl or a silyl group Si(R)3 where the substituents R, either similar or different, are alkyl or aryl groups; R1 and R2, which may be similar or different, are a C1 - C28-alkyl, C2 - C28-alkenyl or alkynyl group or at the same time both an alkenyl and an alkynyl group, with one or several double or triple bonds. According to the invention, a racemic compound having a formula according to (V) is reacted, in the presence of a catalytical lipase enzyme, with anhydride R1COOOR1 or with a compound (III) having the formula R1COOR3 where R1 is the same as above and R3 a vinyl, trifluoroethyl or isopropenyl group. The invention also relates to new intermediate products having formulas according to (I) or (II).</p> |
