发明名称 New derivatives of phosphonic acid, process for their preparation and pharmaceutical compositions containing them
摘要 Compound of formula (I): <IMAGE> in which: R1 represents a hydroxyl group, a linear or branched (C1-C6) alkoxy group or an amino group (substituted or otherwise), R2 represents a substituted or unsubstituted, linear or branched (C1-C6) alkyl group or a (C3-C7) cycloalkyl group, X1 represents -NH-, -O- or -S-, X2 represents -O-, -S- or -NH-, R3 represents a hydrogen atom, a linear or branched (C1-C6) alkyl or a phenyl, R4 represents - a linear or branched (C1-C6) alkyl group still substituted by one or more of the following groups, which are identical or different, hydroxyl, benzyloxy, benzyloxycarbonylamino, amino, linear or branched (C1-C6) mono- or dialkylamino, or acetoxy, - a substituted or unsubstituted (C3-C7) cycloalkyl group, or alternatively <IMAGE> represents the following heterocycle: <IMAGE> in which: n is equal to 0 or 1, R5 represents a hydroxyl or hydroxymethyl group, their enantiomers, their diastereomers and epimers as well as their addition salts with a pharmaceutically acceptable acid or base. Medicinal products.
申请公布号 FR2707089(A1) 申请公布日期 1995.01.06
申请号 FR19930007927 申请日期 1993.06.30
申请人 ADIR CIE 发明人 DE NANTEUIL GUILLAUME;REMOND GEORGESVERBEUREN TONY
分类号 A61K38/00;A61K38/55;A61P9/10;A61P9/12;C07F9/24;C07F9/572;C07K1/06;C07K1/113;C07K1/22;C07K5/06;C07K5/062;(IPC1-7):C07K5/078;A61K38/05 主分类号 A61K38/00
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