发明名称 |
PHOSPHONIC DIESTER DERIVATIVE |
摘要 |
A phosphonic diester derivative represented by general formula (1) and useful as remedies for hyperlipidemia, hypertension, diabetes, and so forth. In said formula, A represents oxygen or sulfur; R<1>, R<2>, R<9> and R<10> represent each independently hydrogen, lower alkoxy, nitro, lower alkyl, halogenated lower alkyl or halogen; R<3> represents phenyl, -B-R<6> (wherein B represents oxygen or sulfur; and R<6> represents hydrogen, lower alkyl, cycloalkyl, phenyl, phenylated lower alkyl wherein the phenyl may be halogenated, phenoxylated lower alkyl, lower-alkoxy carbonyl-substituted lower alkyl, carboxylated lower alkyl or lower alkenyl) or -NR<7>R<8> (wherein R<7> and R<8> represent each independently hydrogen, lower alkyl, amino or cycloalkyl, or R<7> and R<8> are combined together to form lower alkylene); and R<4> and R<5> represent each independently hydrogen or lower alkyl.
|
申请公布号 |
WO9500524(A1) |
申请公布日期 |
1995.01.05 |
申请号 |
WO1994JP00883 |
申请日期 |
1994.05.31 |
申请人 |
OTSUKA PHARMACEUTICAL FACTORY, INC.;KUROGI, YASUHISA;MIYATA, KAZUYOSHI;NAKAMURA, SHIZUO;KONDO, MITSUYOSHI;IWAMOTO, TAKESHI;NABA, CHIEKO;TSUDA, YOSHIHIKO;INOUE, YASUHIDE;KANAYA, JUN;SATO, KEIGO |
发明人 |
KUROGI, YASUHISA;MIYATA, KAZUYOSHI;NAKAMURA, SHIZUO;KONDO, MITSUYOSHI;IWAMOTO, TAKESHI;NABA, CHIEKO;TSUDA, YOSHIHIKO;INOUE, YASUHIDE;KANAYA, JUN;SATO, KEIGO |
分类号 |
C07F9/6512;C07F9/6558;(IPC1-7):C07F9/651;A61K31/675 |
主分类号 |
C07F9/6512 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|