发明名称 .ALPHA.-AMINODICARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE
摘要 Disclosed are .alpha.-aminodicarboxylic acid derivatives of the formula: <IMG> where X is C2-C6-alkylene, -CH=CH- or unacetylated or acetylated -CH2-CHOH-, -CHOH-CHOH- or -CH2-CHNH2-, Y and Z are each an aliphatic hydrocarbon radical of 8 to 30 carbon atoms and n is 1 or 2, and their sodium, potassium and ammonium salts. Also disclosed in a process for the preparation of these compounds that are biodegradable, of low toxicity and useful for the preparation of emulsions, microemulsions and gels. Further disclosed is the use of these compounds as carriers for drugs in the pharmaceutical field.
申请公布号 CA1333719(C) 申请公布日期 1994.12.27
申请号 CA19890591812 申请日期 1989.02.22
申请人 KNOLL AKTIENGESELLSCHAFT 发明人 ROSENBERG, JOERG;GRUENHAGEN, HANS-HEINRICH;LENKE, DIETER
分类号 A61K47/16;A61K9/127;A61K47/18;C07C231/02;C07C233/47;C07C233/49;C07C235/12;C07C237/12;(IPC1-7):C07C235/72;A61K9/42 主分类号 A61K47/16
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