| 发明名称 |
2-saccharinylmethyl heterocyclic carboxylates useful as proteolytic enzyme inhibitors |
| 摘要 |
4-R4-R5-2-Saccharinylmethyl heterocyclic carboxylates, useful in the treatment of degenerative diseases, are prepared by reacting a 4-R4-R5-2-halomethylsaccharin with either a heterocyclic carboxylic acid in the presence of an acid-acceptor or the alkali metal salt of a heterocyclic carboxylic acid.
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| 申请公布号 |
US5376653(A) |
申请公布日期 |
1994.12.27 |
| 申请号 |
US19930109411 |
申请日期 |
1993.08.19 |
| 申请人 |
STERLING WINTHROP INC. |
发明人 |
DUNLAP, RICHARD P.;LATIMER, LEE H.;SUBRAMANYAM, CHAKRAPANI;BELL MALCOLM R;KUMAR VIRENDRA |
| 分类号 |
A61K31/425;A61K9/20;A61K9/48;A61K31/428;A61K31/44;A61P1/00;A61P11/00;A61P35/00;A61P43/00;C07D275/06;C07D417/12;(IPC1-7):A61K31/425;C07D275/04 |
主分类号 |
A61K31/425 |
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