发明名称 IMMUNOREACTIVE REAGENTS EMPLOYING MONOAMINE OXIDASE
摘要 <p>In one aspect this invention describes a non radioactive targeting immunoreagent comprising the residue of a proteinaceous active site of a monoamine oxidase enzyme (MAO), a linking group, and the residue of an immunoreactive material together with a radioactive delivery agent comprising a ligand specific for said MAO receptor moiety, a linking group, and a radioactive agent. In another aspect, this invention describes a non radioactive targeting immunoreagent comprising the residue of a ligand specific for an MAO proteinaceous active site receptor moiety, a linking group, and the residue of an immunoreactive material together with a radioactive delivery agent comprising the residue of an MAO proteinaceous active site receptor moiety, a linking group, and a radioactive agent. These compositions comprise useful systems for the production of an amplification of delivery of the radioactive agent to tumor sites in the therapy and diagnostic imaging of cancer.</p>
申请公布号 WO1994029333(A1) 申请公布日期 1994.12.22
申请号 US1994006424 申请日期 1994.06.07
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