| 发明名称 |
METHOD FOR SPECIFIC SILENCING OF GENES BY DNA METHYLATION |
| 摘要 |
The present invention provides a method for the silencing of specific genes by DNA methylation. The method involves introducing into a cell a single stranded oligonucleotide containing 5-methyl deoxycytosine. The single stranded oligonucleotide has a sequence complementary to a portion of the DNA sequence of the gene to be silenced.
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| 申请公布号 |
WO9429461(A1) |
申请公布日期 |
1994.12.22 |
| 申请号 |
WO1994AU00314 |
申请日期 |
1994.06.10 |
| 申请人 |
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR;HOLLIDAY, ROBIN |
发明人 |
HOLLIDAY, ROBIN |
| 分类号 |
A61K38/00;C07H21/00;C12N15/113;(IPC1-7):C12N15/63;C12N15/10 |
主分类号 |
A61K38/00 |
| 代理机构 |
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代理人 |
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| 主权项 |
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