| 摘要 |
<p>Non-naturally occurring polypeptides are described which stimulate neu receptor phosphorylation and can be prepared by recombinant DNA methods from nucleotide sequences obtained from human cells and tissues. These polypeptides are useful to treat various human conditions involving cells that express the neu receptor and respond to modulation by the polypeptides. Also described are DNA molecules encoding the polypeptides, or analogs of the polypeptides, methods of recombinant DNA production of the polypeptides or analogs from the DNA molecules, biological materials useful in these methods such as expression vectors and transformed or transfected host cells, and pharmaceutical compositions containing the polypeptides.</p> |
